We found it would drop USB drives when transferring large files
Checking Device Manager we would find an error with
ASMedia USB 3.0 eXtensible Host COntroller – 0100 (Microsoft)
on further inspection Devices status was “Windows has stopped this device because it has reported problems (code 43)”
The driver in use was a Microsoft Driver released 9/04/2015
So a driver update is our first point of call
The latest driver we could find at the time of the post was this one from ASUS as ASMedia doesn’t supply their own drivers
This resulted in a driver from ASMedia being used released 12/10/2015, this fixed our drop out issues.